Clinical and epidemiologic characterization of non-infectious uveitis in a university hospital in Paraguay

Autores/as

  • Abel Esteban Figueredo Rojas Universidad Nacional de Asunción, Facultad de Ciencias Médicas, San Lorenzo, Paraguay https://orcid.org/0009-0004-8611-3694
  • Guillermo Raul Vera-Duarte Universidad Nacional de Asunción, Facultad de Ciencias Médicas, San Lorenzo, Paraguay https://orcid.org/0000-0002-3417-256X
  • Claudia Leticia Delgado-Herrera Universidad Nacional de Asunción, Facultad de Ciencias Médicas, San Lorenzo, Paraguay https://orcid.org/0000-0001-8148-1536
  • Martin Fernando Arrúa Caballero Universidad Nacional de Asunción, Facultad de Ciencias Médicas, San Lorenzo, Paraguay
  • Luis González Sanabria Universidad Nacional de Asunción, Facultad de Ciencias Médicas, San Lorenzo, Paraguay https://orcid.org/0000-0002-3989-721X

DOI:

https://doi.org/10.52379/mcs.v8i2.346

Palabras clave:

Uveitis, Non-infectiuos uveitis, clinical characterization, epidemiology

Resumen

Objective: To determine the clinical and epidemiological characteristics of patients with noninfectious uveitis at a university hospital in Paraguay. Methodology: An observational, descriptive, cross-sectional, retrospective study was performed. Consecutive patients who attended the Ophthalmology Service of the Hospital de Clínicas from January 2020 to October 2021 and who were diagnosed with non-infectious uveitis were included. The variables studied were sex, age, origin, reason for consultation, anatomical classification, clinical course, systemic and ocular associations, and bilaterality. Results: A total of 78 medical records of patients meeting the inclusion and exclusion criteria were analyzed. Of the patients, 66.7% were female and 42 (53.8%) were from the Central Department. The anterior anatomical location of uveitis was the most frequent (53.9%), followed in decreasing order by panuveitis, posterior uveitis, and intermediate uveitis. Regarding anterior uveitis, 24 patients (57.1%) had unilateral uveitis, 40 (95.2%) were non-granulomatous, 19 (45.2%) presented an acute clinical course, the most frequent reason for consultation was "red and painful eye" with 15 patients (35.7%), the most frequent systemic association was HLA- B27+ in 16 patients (38.1%). As for panuveitis, 13 patients (50%) were associated with Vogt-Koyanagi-Harada syndrome, and of the latter, two patients were related to rheumatoid arthritis. Conclusion: The clinical and epidemiological patterns observed in this study were largely consistent with those reported in the literature. Notably, the most frequent associations differed from those reported in the literature: HLA-B27+ for anterior uveitis, rheumatoid arthritis for posterior uveitis, and a significant percentage of Vogt-Koyanagi-Harada syndrome among panuveitis cases.

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14-05-2024

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