Muscle strength in adult patients with chronic kidney failure at the National Hospital and Military Hospital in 2021
DOI:
https://doi.org/10.52379/mcs.v6i2.239Keywords:
chronic renal failure, muscle strength, muscle strength dynamometer, anthropometryAbstract
Introduction: muscle strength may decrease in patients with chronic kidney failure due to various causes. Objective: to determine the anthropometric and clinical variables and muscle strength in adult patients with chronic kidney failure. Methodology: an observational, descriptive, cross-sectional design was applied. Men and women, older than 17 years, with chronic kidney failure who attended the National Hospital (Itauguá) and Military Hospital (Asunción), Paraguay, between April and November 2021 were included. Anthropometric, clinical and laboratory variables were determined. Muscle strength was measured with a hand dynamometer. A group of healthy young subjects was used as a control group for the comparison of muscle strength. Descriptive statistics were applied with the statistical program Epi Info 7 ™. The research was approved by the Ethics Committee of the Universidad Privada del Este, Paraguay. Results: 119 subjects entered the study, being 62 (52%) males with a mean age 56 ± 15 years and 57 (48%) females, with a mean age 51 ± 16 years. The mean creatinine clearance was 16.4 ± 17.9 mL / min. The most common etiology was the association of arterial hypertension and diabetes mellitus (45%). The control group included 99 women with a mean age 25 ± 5 years and 51 men with a mean age 26 ± 5 years. When comparing strength between patients and healthy subjects, 66.4% decreased muscle strength was found among patients with chronic renal failure. Conclusion: muscle strength is decreased in 66.4% of chronic kidney failure patients. Early detection and early treatment of muscle strength deficit is recommended in this group of patients.
Downloads
References
Afsar B, Siriopol D, Aslan G, Eren OC, Dagel T, Kilic U, et al. The impact of exercise on physical function, cardiovascular outcomes and quality of life in chronic kidney disease patients: a systematic review. Int Urol Nephrol. 2018;50(5):885–904. http://dx.doi.org/ 10.1007/s11255-018-1790-4.
Iman Y, Harasemiw O, Tangri N. Assessing physical function in chronic kidney disease. Curr Opin Nephrol Hypertens. 2020;29(3):346–50. http://dx.doi.org/ 10.1097/MNH.0000000000000594.
Segura-Ortí E, Gordon PL, Doyle JW, Johansen KL. Correlates of physical functioning and performance across the spectrum of kidney function. Clin Nurs Res. 2018;27(5):579–96. http://dx.doi.org/ 10.1177/1054773816689282.
Mori K, Nishide K, Okuno S, Shoji T, Emoto M, Tsuda A, et al. Impact of diabetes on sarcopenia and mortality in patients undergoing hemodialysis. BMC Nephrol. 2019;20(1):105. http://dx.doi.org/ 10.1186/s12882-019-1271-8.
Leal VO, Mafra D, Fouque D, Anjos LA. Use of handgrip strength in the assessment of the muscle function of chronic kidney disease patients on dialysis: A systematic review. Nephrol Dial Transplant. 2011;26(4):1354–60. http://dx.doi.org/ 10.1093/ndt/gfq487.
Carrero JJ, Johansen KL, Lindholm B, Stenvinkel P, Cuppari L, Avesani CM. Screening for muscle wasting and dysfunction in patients with chronic kidney disease. Kidney Int. 2016;90(1):53–66. http://dx.doi.org/10.1016/j.kint.2016.02.025.
Miller J, Wells L, Nwulu U, Currow D, Johnson MJ, Skipworth RJE. Validated screening tools for the assessment of cachexia, sarcopenia, and malnutrition: A systematic review. Am J Clin Nutr. 2018;108(6):1196–208. http://dx.doi.org/ 10.1093/ajcn/nqy244.
Esteves CL, Ohara DG, Matos AP, Ferreira VTK, Iosimuta NCR, Pegorari MS. Anthropometric indicators as a discriminator of sarcopenia in community-dwelling older adults of the Amazon region: a cross-sectional study. BMC Geriatr. 2020;20(1):518. http://dx.doi.org/ 10.1186/s12877-020-01923-y.
Cruz-Jentoft AJ, Bahat G, Bauer J, Boirie Y, Bruyère O, Cederholm T, et al. Sarcopenia: revised European consensus on definition and diagnosis. Age Ageing. 2019;48(1):16–31. http://dx.doi.org/ 10.1093/ageing/afy169.
Kim KM, Jang HC, Lim S. Differences among skeletal muscle mass indices derived from height-, weight-, and body mass index-adjusted models in assessing sarcopenia. Korean J Intern Med. 2016;31(4):643–50. http://dx.doi.org/ 10.3904/kjim.2016.015.
Canda Moreno AS. Puntos de corte de diferentes parámetros antropométricos para el diagnóstico de sarcopenia. Nutr Hosp. 2015;32(2):765–70. http://dx.doi.org/ 10.3305/nh.2015.32.2.9193.
Pár A, Hegyi J, Váncsa S, Pár G. Sarcopenia – 2021. Orv Hetil. 2021;62:3–12. http://dx.doi.org/ 10.1556/650.2021.32015.
Hwang SH, Lee DH, Min J, Jeon JY. Handgrip strength as a predictor of all-cause mortality in patients with chronic kidney disease undergoing dialysis: A meta-analysis of prospective cohort studies. J Ren Nutr. 2019;29(6):471–9. http://dx.doi.org/ 10.1053/j.jrn.2019.01.002.
Zhou Y, Hellberg M, Svensson P, Höglund P, Clyne N. Sarcopenia and relationships between muscle mass, measured glomerular filtration rate and physical function in patients with chronic kidney disease stages 3-5. Nephrol Dial Transplant. 2018;33(2):342–8. http://dx.doi.org/ 10.1093/ndt/gfw466.
Souza VA, Oliveira D, Barbosa SR, Corrêa JODA, Colugnati FAB, Mansur HN, et al. Sarcopenia in patients with chronic kidney disease not yet on dialysis: Analysis of the prevalence and associated factors. PLoS One. 2017;12(4):e0176230. http://dx.doi.org/ 10.1371/journal.pone.0176230.
Gil APP, Lunardi A, Santana F, Bergamim J, Sarmento L, Cristelli M, et al. Impact of renal transplantation and immunosuppressive therapy on muscle strength, functional capacity, and quality of life: A longitudinal study. Transpl Proc. 2020;52(5):1279–83. http://dx.doi.org/ 10.1016/j.transproceed.2020.02.038.
Xu X, Yang Z, Ma T, Li Z, Chen Y, Zheng Y, et al. The cut-off values of handgrip strength and lean mass index for sarcopenia among patients on peritoneal dialysis. Nutr Metab (Lond). 2020;17:84. http://dx.doi.org/ 10.1186/s12986-020-00506-3.
Peralta R, Gamarra Fleitas F, Gómez Fernández MN, Vaesken Rojas J, Frutos López RD, Galeano Vera SM. Características clínicas de la anemia en la enfermedad renal crónica de pacientes del Hospital Nacional en 2018. Rev virtual Soc Parag Med Int. 2019;6(1):11–20. http://dx.doi.org/ 10.18004/rvspmi/2312-3893/2019.06(01)11-020.
Webster AC, Nagler E V., Morton RL, Masson P. Chronic kidney disease. Lancet. 2017;389(10075):1238–52. http://dx.doi.org/ 10.1016/S0140-6736(16)32064-5.
Bocanegra-Becerra Y, Cornejo-Votez E, García-Alrcón S, Zalazar-Campos C, Sisniegas-Pajuelo C, Pajuelo-García D, et al. Valor diagnóstico de la circunferencia de brazo, muslo y pierna en el estado nutricional del adulto mayor en el hospital Almanzor Aguinaga Asenjo 2011. Rev Cuerpo Med HNAAA. 2012;5(2):11–4. Disponible en: https://docs.bvsalud.org/biblioref/2020/03/1051909/v5-n2-abr-jun-2012-p11-14.pdf
Pereira RA, Cordeiro AC, Avesani CM, Carrero JJ, Lindholm B, Amparo FC, et al. Sarcopenia in chronic kidney disease on conservative therapy: Prevalence and association with mortality. Nephrol Dial Transplant. 2015;30(10):1718–25. http://dx.doi.org/ 10.1093/ndt/gfv133.
García Salinas HA, Barreto RS, Gavilán Herreros JA, Insfrán Echauri EM, Sisa Ferreira CG, Santa Cruz Segovia FV. Detección de enfermedad renal crónica oculta en personas del Bañado Sur de Asunción. Rev virtual Soc Parag Med Int. 2015;2(1):23–30. http://dx.doi.org/ 10.18004/rvspmi/2312-3893/2015.02(01)23-030.
Real Delor R, Gamez Cassera MA, Redes Zeballos ML, Martínez Urizar M, Aguilera Iriarte GA, Oviedo Velázquez G, et al. Adherencia al tratamiento antihipertensivo en adultos de Unidades de Salud Familiar del Paraguay: estudio multicéntrico. Rev salud publica Parag. 2021;11(2):35–41. http://dx.doi.org/ 10.18004/rspp.2021.diciembre.35
Johansen KL, Dalrymple LS, Delgado C, Kaysen GA, Kornak J, Grimes B, et al. Association between body composition and frailty among prevalent hemodialysis patients: A US renal data system special study. J Am Soc Nephrol. 2014;25(2):381–9. http://dx.doi.org/ 10.1681/ASN.2013040431.
Delgado C, Doyle J, Johansen K. Association of frailty with body composition among patients on hemodialysis. J Ren Nutr. 2013;23(5):356–62. http://dx.doi.org/ 10.1053/j.jrn.2013.02.010.
Shamliyan T, Talley KMC, Ramakrishnan R, Kane RL. Association of frailty with survival: A systematic literature review. Ageing Res Rev. 2013;12(2):719–36. http://dx.doi.org/ 10.1016/j.arr.2012.03.001.
Johansen KL, Dalrymple LS, Glidden D, Delgado C, Kaysen GA, Grimes B, et al. Association of performance-based and self–reported function–based definitions of frailty with mortality among patients receiving hemodialysis. Clin J Am Soc Nephrol. 2016;11(4):626–32. http://dx.doi.org/ 10.2215/CJN.03710415.
Lee SY, Yang DH, Hwang E, Kang SH, Park SH, Kim TW, et al. The prevalence, association, and clinical outcomes of frailty in maintenance dialysis patients. J Ren Nutr. 2017;27(2):106–12. http://dx.doi.org/ 10.1053/j.jrn.2016.11.003.
Nitta K, Hanafusa N, Tsuchiya K. Role of frailty on outcomes of dialysis patients. Contrib Nephrol. 2018;195:102–9. http://dx.doi.org/ 10.1159/000486940.
Nixon A, Wilkinson T, Young H, Taal M, Pendleton N, Mitra S, et al. Symptom-burden in people living with frailty and chronic kidney disease. BMC Nephrol. 2020;21(1):411. http://dx.doi.org/ 10.1186/s12882-020-02063-6.
Kraut JA, Madias NE. Adverse effects of the metabolic acidosis of chronic kidney disease. Adv Chronic Kidney Dis. 2017;24(5):289–97. http://dx.doi.org/ 10.1053/j.ackd.2017.06.005.
Casals-Vázquez C, Suárez-Cadenas, E Estébanez Carvajal F, Aguilar Trujillo, MP Jiménez Arcos, MM Vázquez Sáchez M. Relación entre calidad de vida, actividad física, alimentación y control glucémico con la sarcopenia de adultos mayores con diabetes mellitus tipo 2. Nutr Hosp. 2017;34(5):1198–204. http://dx.doi.org/ 10.20960/nh.1070.
Roy Torales T, Peralta Giménez R, González Aquino A, Backer W, Dias Camillo I, Ilatas Zapata H, et al. Índice de comorbilidad de Charlson aplicado a pacientes de Medicina Interna: estudio multicéntrico. Rev virtual Soc Parag Med Int. 2019;6(2):47–56. http://dx.doi.org/ 10.18004/rvspmi/2312-3893/2019.06.02.47-056.
López Plaza B, Gómez Candela C, Bermejo LM. Problemática nutricional relacionada con la fragilidad y la sarcopenia en personas de edad avanzada. Nutr Hosp. 2019;36(3):49–52. http://dx.doi.org/ 10.20960/nh.02809.
Cigarroa I, Barriga R, Michéas C, Zapata-Lamana R, Soto C, Manukian T. Efectos de un programa de ejercicio de fuerza-resistencia muscular en la capacidad funcional, fuerza y calidad de vida de adultos con enfermedad renal crónica en hemodiálisis. Rev Méd Chile. 2016;144(7):844–52. http://dx.doi.org/ 10.4067/S0034-98872016000700004.
Downloads
Published
Issue
Section
License
Copyright (c) 2022 Raúl Emilio Real Delor, Tatiana Roy-Torales, Jorge David Brítez-Mendoza , Domingo Guzmán Encina-Villagra , José Luis Giménez, Maria José Gómez, Eliana María González Hermosa, Nilda Andrea Insfrán Cabrera, Valeria Emilia Mareco Caballero, Jessica Shirleni Pérez Alves, Yenniffer Marlene Ramírez Colmán, Elio David Ruiz Díaz Ojeda, Juan José Torales-Velaztiqui
This work is licensed under a Creative Commons Attribution 4.0 International License.