Effectiveness of empirical therapy with Cefotaxime and Ceftriaxone in medical and surgical services of the hospital "Dr. Benigno Sanchez" of Quillacollo
DOI:
https://doi.org/10.52379/mcs.v8i2.374Keywords:
antimicrobials, effectiveness, empirical drug treatmentAbstract
Introduction. Inappropriate use of antibiotics contributes to the increase in bacterial resistance; resistant strains are very difficult to treat with available antibiotics. Objetive. To evaluate the effectiveness of empirical pharmacological treatment with Cefotaxime and Ceftriaxone in clinical and surgical services of the “Dr. Benigno Sánchez” from Quillacollo, during the 2022 administration. Methodology. It is an observational study of analytical type, case-control subtype, prospective longitudinal. The population was 1395 patients, obtaining a sample of 884 patients, subdividing cases n=741 and controls n=126 into groups. Results. In the surgical service, the frequency among men and women was 45 % and 55 % respectively; 73 % of the total did not present underlying diseases, 90 % of the total had a hospitalization of less than one week with 95 % improvement without significant difference between cases and controls. In the clinical service, 60 % were women, the rest men, 50 % of the total did not present underlying diseases, 78 % of the total had a hospitalization of less than a week with 85 % improvement without significant difference between cases and controls. Discussion. The sociodemographic characteristics, the present study identified that in the surgical service the average age was 43 years, of these 45 % were men and 55 % women, however in the clinical service, the average age was 55 years, 60 % women the rest men. The present study identified that, in the surgical service, 95 % of the cases have improvement, without there being a relationship between the therapy used or not. In the clinical service, an 85 % improvement was seen with no difference between the groups.There is no significant difference between the groups, in medical surgical services, with respect to improvement.
Downloads
References
Fleitas Estévez Andrés Samuel. Terapia antimicrobiana utilizada de forma empírica y prudente en los pacientes con enfermedades vasculares periféricas. Revista Cubana de Angiología y Cirugía Vascular. 2015; 16(2):190-204. URL
Bisso-Andrade A. Resistencia a antimicrobianos. Rev Soc Peru Med Interna. 2018;31(2):50-59. URL
Organización Mundial de la Salud. Organización Mundial de la Salud. 2019. URL
Vallejo-Pazmiño GI; Andrande-Tacuri CF et al. Resistencia de cepas de Staphylococcus aureus aislados en ambientes nosocomiales. VIVE. Revista de Investigación en Salud. 2022;5(13):22–34. https://doi.org/10.33996/revistavive.v5i13.127
Mella - M S., Zemelman - M C., Bellot H., Dominguez M., Gonzalez - R G. Zemelman - Z R. Propiedades microbiológicas, clasificación y relación estructura-actividad de cefalosporinas e importancia de las cefalosporinas de cuarta generación. Rev Chil Infect. 2001; 18(1): p. 7-19. http://dx.doi.org/10.4067/S0716-10182001000100002
Hernández Loriga Wildo, Padrón Álvarez Jorge Enrique, Pérez Pedraza Alfredo, González Díaz Judiet, Riesgo Mayea Liudmila, Barrabí Arango Ileana et al . Staphylococcus aureus resistente a meticilina. Rev Cubana Med Trop. 2018;70(2):1-9. URL
Boutier-P. GI. Mapa epidemiológico de resistencia antimicrobiana de los agentes bacterianos aislados en el hospital santa bárbara. Rev. Bio Scientia. 2018;1(2):1-12. URL
Hernandez-Sampieri R, Mendoza-Torres CP. Metodología de la Investigación: las rutas cuantitativa, cualitativa y mixta. Primera. ed. McGRAW-HILL. , editor. Mexico D.F.: Interamericana editores, S.A. DE C.V.; 2018. URL
Díaz-Portillo J. Guía Práctica del Curso de Bioestadística Aplicada a las Ciencias de la Salud. Segunda ed. Humanos SGdGEyR, editor. Madrid.: Instituto Nacional de Gestión Sanitaria; 2011. URL
César Augusto Bernal Torres. Metodología de la investigación administración, economía, humanidades y ciencias sociales. Tercera edición PEARSON EDUCACIÓN, Colombia, 2010. URL
Kirkwood B, Sterne J. Essential Medical Statistics. Oxford: Blackwell Publishing Company. Segunda ed.; 2006. URL
SPSS Base 10.0. (2000) Manual del usuario del sistema básico de IBMSPSS Statistics19. Chicago: SPSS Inc. Licensed Materials. URL
Arredondo-Bruce A, Peña-Pérez D. Caracterización del uso de las cefalosporinas en un servicio hospitalario de medicina interna. Revista Electrónica Dr. Zoilo E. Marinello Vidaurreta. 2019;44(2). URL
Resurrección-Delgado C, Chiappe-Gonzalez A, BolarteEspinoza J, Martínez-Dionisio L, Muñante-Meneses R, VicenteLozano Y, et al. Uso de antibióticos en pacientes internados en un hospital nacional de Lima, Perú. Rev Peru Med Exp Salud Publica. 2020;37(4):620-6. https://doi.org/10.17843/rpmesp.2020.374.5073
Clara, L; Angeleri, P; Blugerman, G; Biondi, H; Carbone, E; Chattas, A; Colombini, A; Cornistein, W; Daciuk, L; Del Castillo, M; Fernández Garcés, A. Guía de profilaxis antibiótica quirúrgica. Primera ed. Heduan lpac, editor. Buenos Aires, Argentina: editorial Océano Argentina S.A. 2017. URL
Hernández Loriga Wildo, Padrón Álvarez Jorge Enrique, Pérez Pedraza Alfredo, González Díaz Judiet, Riesgo Mayea Liudmila, Barrabí Arango Ileana et al . Staphylococcus aureus resistente a meticilina. Rev Cubana Med Trop. 2018;70(2):1-9. URL
Loncón-Coliñir FE., Jiron M., Ávila-Oesterle F. Uso de antibióticos de segunda línea en pacientes hospitalizados en sala de un hospital universitario de alta complejidad. Santiago de Chile 2018. URL
Marcela Nastro ¿Qué podemos hacer para combatir la multirresistencia? Rev Argent Microbiol. 2019;51(1):1-2. https://doi.org/10.1016/j.ram.2019.02.001
Ávila Fernanda, Luppi Mario, Gaete Pablo, Rivas Alejandra, Silva Francisco, Olivares Roberto. Cambios en las prescripciones y el consumo de antimicrobianos, luego de la implementación de recomendaciones de uso: experiencia en un hospital universitario. Rev. chil. infectol. 2019;36(3):253-264. http://dx.doi.org/10.4067/S0716-10182019000300253
Downloads
Published
Issue
Section
License
Copyright (c) 2024 Julio César Orozco Crespo
![Creative Commons License](http://i.creativecommons.org/l/by/4.0/88x31.png)
This work is licensed under a Creative Commons Attribution 4.0 International License.