Preliminary report on the sociodemographic and clinical characteristics of patients with hematologic malignancies: experience of a university hospital

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DOI:

https://doi.org/10.52379/mcs.v7i1.273

Keywords:

hemopathies, sociodemographic characteristics, clinical characteristics, lymphomas

Abstract

Introduction: due to their wide clinical and biological diversity, it is of great importance for the physician to know how patients diagnosed with a hematological malignancy present. Objective: to describe the sociodemographic and clinical characteristics of patients diagnosed with a hematological malignancy who consulted at a University Hospital in Paraguay. Methodology: observational, retrospective, descriptive, cross-sectional, retrospective, descriptive, cross-sectional study, with non-probabilistic sampling of consecutive cases. We included adult patients, of both sexes, registered in the Hematology file of the Hospital de Clínicas of the Faculty of Medical Sciences of the National University of Asunción (Paraguay), with diagnosis confirmed by pathological anatomy of a hematological neoplasm, according to the classification of the World Health Organization, during the period from January 2019 to August 2021. Sociodemographic and clinical variables were studied. Results: 129 patients were studied. Fifty-eight percent were male. The mean age of the patients was 50.3±17.38. Most of the patients were from the Central Department of Paraguay (56.58 %). Most of the patients (n=37) were diagnosed with a non-Hodgkin's lymphoma or a neoplasm with plasma cell origin (n=32). The average time from symptom onset to consultation was 3.5 months. The most reported symptom was asthenia (35%). Pallor was the most frequent positive finding on physical examination. The most frequent comorbidities were arterial hypertension (39.44%) and diabetes mellitus (15.59%). Discussion: the typical patient with a hemopathy who consults at the Hospital de Clínicas is male, over 50 years of age, from the Central Department, consults for asthenia, presents pallor on physical examination and has taken more than 3 months to consult. He has been diagnosed with non-Hodgkin's lymphoma and has cardiovascular or metabolic comorbidities.

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References

Rodríguez Díaz-Regañón I. Capítulo 65: Neoplasias Hematológicas. En: Tratado de Geriatría para residentes. Sociedad Española de Geriatría; 2007.

Alaggio R, Amador C, Anagnostopoulos I, Attygalle AD, Araujo IB de O, Berti E, et al. The 5th edition of the World Health Organization Classification of Haematolymphoid Tumours: Lymphoid Neoplasms. Leukemia. 2022;36(7):1720–48. https://doi.org/10.1038/s41375-022-01620-2

Zeidan AM, Bewersdorf JP, Buckstein R, Sekeres MA, Steensma DP, Platzbecker U, et al. Finding consistency in classifications of myeloid neoplasms: a perspective on behalf of the International Workshop for Myelodysplastic Syndromes. Leukemia. 2022;36(12):2939–46. https://doi.org/10.1038/s41375-022-01724-9

Vardiman JW, Thiele J, Arber DA, Brunning RD, Borowitz MJ, Porwit A, et al. The 2008 revision of the World Health Organization (WHO) classification of myeloid neoplasms and acute leukemia: rationale and important changes. Blood. 2009;114(5):937–51. https://doi.org/10.1182/blood-2009-03-209262

Moraleda J. Capítulo 16: Síndromes Linfoproliferativos con expresión leucémica. En: Pregrado de Hematología. 4a ed. España: Editorial Luzán; 2017.

Sans M, Carreras E. Capítulo: Neoplasias del sistema linfoide. Clasificación. En: Manual práctico de hematología clínica. España: Amgen; 2017.

Pino D, Segura MS, Suárez VM, Hernández IC, Abraham CM. Aspectos generales de algunas entidades dentro de los síndromes linfoproliferativos crónicos: la leucemia linfoide crónica. Revista Cubana de Hematología, Inmunología y Hemoterapia. 2017;33(4). URL.

Fariña Bellenzier M. Frecuencia de mortalidad en pacientes onco-hematológicos del Hospital Nacional de Itauguá. [Itapúa]: Universidad Nacional de Itapua; 2014.

Zeilinger EL, Lubowitzki S, Unseld M, Schneckenreiter C, Heindl D, Staber PB, et al. The impact of COVID?19 on cancer care of outpatients with low socioeconomic status. Int J Cancer. 2022;151(1):77–82. https://doi.org/10.1002%2Fijc.33960

Rodríguez-Matos G. Hemopatías malignas en sancti spíritus. estudio de incidencia en 5 años. Revista Cubana de Hematología, Inmunología y Hemoterapia. 2017;33(S1):1–5. URL.

Aguado-Vázquez T. Epidemiología y subtipos de neoplasias hematológicas en pacientes atendidos en un Hospital Privado de la Ciudad de México, durante los años 2008-2015. México: Universidad Nacional Autónoma de México; 2016.

Cotto JJR, Campozano JPT, Feijoo LEJ, Peña GRP, Briones RMQ. Caracterización epidemiológica de las Neoplasias del Sistema Hematopoyético atendidos en el Instituto Oncológico Nacional-SOLCA Guayaquil: Artículo Original. Oncología (Ecuador). 2021;31(1):46–55. https://doi.org/10.33821/544

Alonso Mariño OL, Alonso Mariño AL, Miranda Chaviano J. Caracterización clínico-epidemiológica de los linfomas en un período de cinco años en Villa Clara. Medicentro Electrónica. 2015;19(1):13–20. URL.

Hernández LA, Mariño OLA, Mariño ALA. Epidemiología y subtipos de neoplasias linfoides. Acta Médica del Centro. 2018;12(3):286–92. URL.

Ron-Guerrero CS, Ron-Magaña AL, Medina-Palacios CL, López-Flores F. Epidemiología de los linfomas del Centro Estatal de Cancerología de Nayarit. Rev Hematol Mex. 2015;16(2):109–14. URL.

Martínez-Acosta G, Rubio-Anguiano BL, López-Salvio YM, Guillen-Rivera SL, Nava-Zavala AH, Rubio-Jurado B. Aspectos geriátricos en las neoplasias hematológicas. Residente. 2017;12(1):4–17. URL.

Published

02/01/2023

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