Situación epidemiológica de las anomalías congénitas en Paraguay en el periodo 2017-2021

Sara Aguilar-Coronel; Florencia del Puerto; Moisés Ó. Fiesco-Roa; Juan Mereles; Margarita Samudio

doi:10.52379/mcs.v9.523

Epidemiological situation of congenital anomalies in Paraguay in the period 2017-2021

Authors

Sara Aguilar-Coronel Instituto de Investigaciones en Ciencias de la Salud https://orcid.org/0000-0002-8167-6437
Florencia del Puerto Instituto de Investigaciones en Ciencias de la Salud https://orcid.org/0000-0003-0631-8805
Moisés Ó. Fiesco-Roa Laboratorio de Citogenética. Instituto Nacional de Pediatría. CDMX-México. https://orcid.org/0000-0002-8123-5068
Juan Mereles Universidad Nacional de Asunción. Facultad de Ciencias Exactas y Naturales, San Lorenzo, Paraguay https://orcid.org/0000-0001-7727-8500
Margarita Samudio Universidad del Pacífico, Asunción, Paraguay https://orcid.org/0000-0003-2813-218X

DOI:

https://doi.org/10.52379/mcs.v9.523

Keywords:

Congenital anomalies, congenital heart diseases, Paraguay

Abstract

Introduction: Congenital anomalies (CA) are structural or functional defects that occur during fetal development and are detected before, during or after birth. They represent an important public health problem due to their contribution to neonatal morbidity and mortality. Objective: To analyze the epidemiological situation of congenital anomalies in Paraguay from 2017-2021, in terms of prevalence and mortality using public data. Methods: Ecological study with data obtained from the digital platform of the Vital Statistics Computer Subsystem (SSIEV) and the Latin American Network of Congenital Malformations (ReLAMC) for the period 2017-2021. Results: Data from 273,239 births were analyzed, cardiac and large vessel anomalies were the most prevalent, accounting for 64% of all CAs. In terms of mortality, 2090 of 2639 deaths occurred in the first 11 months of life. The Central department had the highest frequency of deaths related to CA, with 881 deaths, representing 33.38% of the total. Conclusion: Congenital anomalies, particularly those related to heart defects, represent an important cause of morbidity and mortality in Paraguay. The most affected population was the pediatric population, and a high prevalence of heart and ear defects was observed. These results highlight the need to improve diagnostic and treatment capacities to reduce mortality associated to congenital anomalies.

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References

1. Chimah OU, Emeagui KN, Ajaegbu OC, et al. Congenital malformations: Prevalence and characteristics of newborns admitted into Federal Medical Center, Asaba. Health Sci Rep. 2022;5(3). https://doi.org/10.1002/hsr2.599

2. Elghanmi A, Razine R, Jou M, Berrada R. Congenital Malformations among Newborns in Morocco: A Retrospective Study. Pediatr Rep. 2020;12(1):7405. https://doi.org/10.4081/pr.2020.7405

3. Orioli IM, Dolk H, Lopez-Camelo J, Groisman B, Benavides-Lara A, Gimenez LG, et al. The Latin American network for congenital malformation surveillance: ReLAMC. American Journal of Medical Genetics Part C: Seminars in Medical Genetics. 2020;184(4):1078–91. https://doi.org/10.1002/ajmg.c.31872

4. Muga R, Mumah S, Juma P. Congenital malformations among newborns in Kenya. African Journal of Food, Agriculture, Nutrition and Development. 2009;9(3). https://doi.org/10.4314/ajfand.v9i3.43008

5. Martínez-Frías ML. Características generales de los defectos congénitos, terminología y causas. SEMERGEN - Medicina de Familia. 2010;36(3):135-139. https://doi.org/10.1016/j.semerg.2009.12.012

6. Putti P, Ginecotocológica C, Briozzo L, Prenatal D, De Opinión A. Defectos congénitos y patologías incompatibles con la vida extrauterina. Rev Méd Urug. 2016;32(3):218-223. URL

7. Giraldo-Villegas E, Jaimes-Montaña IC. Malformaciones congénitas: incidencia y prevalencia en el departamento de Caldas, Colombia 2016-2017. MedUNAB. 2022;25(2):193-216. https://doi.org/10.29375/01237047.4129

8. Ministerio de Salud Pública y Bienestar Social. Programa Nacional de Prevención de Defectos Congénitos. URL

9. ReLAMC. Red Latinoamericana de Malformaciones Congénitas. URL

10. Ministerio de Salud Pública y Bienestar Social, Sub Sistema de Estadisticas Vitales (SSIEV). URL

11. Orphanet. Síndrome de Down. URL

12. Ministerio de Salud Pública y Bienestar Social. Licencia de uso de la información pública. URL

13. Larrandaburu M, Vieira MT, Luiz F, Nacul L, Schuler L. Anomalías congénitas frecuentes en Uruguay entre 2011 y 2014: importancia de un registro para la evaluación de las necesidades de salud. Arch Pediatr Urug. 2022;93(1). https://doi.org/10.31134/ap.93.1.12

14. Groisman B, Bidondo MP, Barbero P, Gili JA, Liascovich R. RENAC: Registro Nacional de Anomalías Congénitas de Argentina. Arch Argent Pediatr. 2013;111(6):0. http://dx.doi.org/10.5546/aap.2013.484

15. Acero González JA, Angulo Casalis A, Martínez Buitrago JS, Soto Beltrán J. Caracterización de Malformaciones Congénitas En Recién Nacidos En Siete Hospitales de Bogotá y Un Hospital de Tunja 2016-2018. Universidad del Rosario; 2019. https://doi.org/10.48713/10336_19818

16. Khairy P, Silka MJ, Moore JP, et al. Sudden cardiac death in congenital heart disease. Eur Heart J. 2022;43(22):2103-2115. https://doi.org/10.1093/eurheartj/ehac104

17. Ministerio de Salud Pública y Bienestar Social. Boletin de Vigilancia Nro 5 Enfermedades no Transmisibles – Dirección de Enfermedades no Transmisibles. URL

18. El Koumi MA, Al Banna EA, Lebda I. Pattern of Congenital Anomalies in Newborn: A Hospital-Based Study. Pediatr Rep. 2013;5(1):20. https://doi.org/10.4081/pr.2013.e5

19. Anomalías congénitas tasa de muerte por país. 5, 2024. URL

20. Dirección Nacional de Estadísticas, Encuestas y Censos. Resultados Censo 2022. URL