Mortalidad en adultos con COVID-19: experiencia de la Unidad de Cuidados Intensivos de un Hospital de Tercer Nivel de Paraguay

Paola Pusineri Escobar; Manuel González Gómez; Iván Barrios; Julio Torales

doi:10.52379/mcs.v7i1.272

Mortality in adults with COVID-19: experience of the Intensive Care Unit of a Third Level Hospital in Paraguay

Authors

Paola Pusineri Escobar Universidad Nacional de Asunción, Facultad de Ciencias Médicas, San Lorenzo, Paraguay https://orcid.org/0000-0002-3406-1448
Manuel González Gómez Universidad Nacional de Asunción, Facultad de Ciencias Médicas, San Lorenzo, Paraguay https://orcid.org/0000-0003-1485-1490
Iván Barrios Universidad Nacional de Asunción, Facultad de Ciencias Médicas, Santa Rosa del Aguaray, Paraguay https://orcid.org/0000-0002-6843-7685
Julio Torales Universidad Nacional de Asunción, Facultad de Ciencias Médicas, San Lorenzo, Paraguay https://orcid.org/0000-0003-3277-7036

DOI:

https://doi.org/10.52379/mcs.v7i1.272

Keywords:

COVID-19, mortality, mechanical ventilation, bacterial infection, hemodialysis

Abstract

Introduction: Several factors may influence mortality in patients hospitalized with COVID-19. Objective: This research aimed to determine mortality and associated factors in adults with COVID-19 hospitalized in the intensive care unit of a Third Level Hospital in Paraguay. Methodology: Observational, descriptive of cross-association, cross-sectional, and retrospective study. We included medical records of adult patients, of both sexes, who had a confirmed diagnosis (by antigen and/or PCR test) of SARS-CoV-2 infection and who were hospitalized in the intensive care unit of a Third Level General Hospital in Paraguay. Results: We included 116 patients, 54% of whom were male. The mean age was 57 ± 12.9 years. Of participants, 51% had hypertension and 29% diabetes mellitus. Mechanical ventilation was required in 85% of the patients. Of ventilated patients, 75% had a fatal outcome. A statistically significant association was found between the presence of bacterial infections and hemodialysis requirement and fatal outcome (p=0.0074 and p=0.00011, respectively). The mean age of the deceased patients was 59.5 years, while the group of patients discharged from the intensive care unit had a mean age of 54.2 years. The difference between these ages in relation to death was significant, with a p<0.05. Discussion: Overall mortality due to COVID-19 was more than 6 per 10 patients, being higher in those patients with ventilation. Those patients who presented bacterial superinfection or required hemodialysis during hospitalization had a worse outcome compared to patients who did not present this type of complications.

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