Clinical-epidemiological characterization and etiological agents of severe acute respiratory infections in adults in Paraguay

Authors

  • Dora Montiel-Jarolin Hospital Nacional de Itauguá, Itauguá, Paraguay
  • Margarita Samudio Universidad del Pacífico, Asunción, Paraguay https://orcid.org/0000-0003-2813-218X
  • Karin Volkart Hospital Nacional de Itauguá, Itauguá, Paraguay
  • Rosa Leguizamón Hospital Nacional de Itauguá, Itauguá, Paraguay
  • Magali Jarolin Hospital Nacional de Itauguá, Itauguá, Paraguay
  • Estela Torres Hospital Nacional de Itauguá, Itauguá, Paraguay
  • Luis Sánchez Hospital Nacional de Itauguá, Itauguá, Paraguay https://orcid.org/0000-0001-6665-7126

DOI:

https://doi.org/10.52379/mcs.v8i2.358

Keywords:

respiratory viruses, acute respiratory failure, mortality

Abstract

Introduction: Sentinel Surveillance of Severe Acute Respiratory Infections (SARI) includes the monitoring and characterization of hospitalized cases. Objective: To describe the clinical-epidemiological characteristics and etiological agents of adults with SARI in a sentinel hospital in Paraguay. Methodology: Observational, descriptive, cross-sectional study, with retrospective data collection, of adult patients with SARI hospitalized at the National Hospital of Itauguá between June 2022 and August 2023. The information was taken from the database of the National System of Epidemiological surveillance. Results: The data of 1598 patients with SARI were analyzed, 820 men (51.3%), 875 (54.8%) aged 60 or older, 1054 (66.0%) from the Central department. 79.2% (n=1265) of patients had some risk factor or comorbidity, 764 with hypertension (47.8%). 38.5% (n=632) were admitted to the ICU and mortality was 34.7% (n=554). SARSCoV-2 was confirmed in 13.8% (n=353), rhinovirus (1.7%), influenza A (1.5%), influenza B (0.6%), parainfluenza 3 (0.6%), RSV (0.2%), bocavirus (0.4%) and Influenza AH1N1 (0.6%). There was a significantly higher frequency of deaths in those aged 60 years and over (40.7%), with some risk factor (35.5% vs 25.9%), and in those confirmed with covid-19 (38.2% % vs 30.5%). Conclusion: SARSCoV-2 continues to be the main etiological agent of SARI in a sentinel hospital in Paraguay. Continued knowledge of the epidemiology and viral agents involved is crucial to developing effective prevention and treatment strategies.

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Published

05/14/2024

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